Posted by floatingbridge on March 15, 2010, at 23:30:14
In reply to Re: Stimulants helping more over time?, posted by West on March 14, 2010, at 10:35:53
West, are you saying that ritalin is similar to concerta? I thought concerta was like strattera?
Dex broke my depression--however there is the cyclic low mood as it wears off. Is that what you refer to as 'mood-degrading'?
And it certainly doesn't work like it used to. Have you had diminished effectiveness with concerta?
> I would echo what linkage pointed out about depressive reactions and would personally not do well on any stimulant if not already stabilised on an antidepressant.
>
> Immediate release ritalin and dex are not worth the hassle imo. Concerta is different. I don't notice it wearing off anymore. Dex-amp degrades mood whereas mph supports it. D-threo-mph,
it's metabolite shows clinically relevant agonism of 5-Ht(1a) in guinea pigs, useful if taken with SSRis.
>
> Add a 5ht(2c) antagonist and you're increasing NA/DA firing.
poster:floatingbridge
thread:939206
URL: http://www.dr-bob.org/babble/20100305/msgs/939678.html