Posted by ace on April 5, 2010, at 8:47:00
In reply to Re: To the VETERANS on this board MAOI Question » Ron Hill, posted by mike0388 on April 3, 2010, at 15:46:50
> Thank you Ron Hill for the response. What I found most interesting from the link is, it says once you reach the max. benefit from Nardil, to decrease over several weeks, even down to 1 15mg pill a day? Is this because the nardil is in your system already and there is no need for multiple pills?
I don't know why they state that. You have to achieve what's called "MAO inhibition" (-%80)
A reduction in dose would lessen this, thus reducing (or obliterating) the therapeutic effects.I have not seen any evidence to support this maintenance dose recommendation
> DOSAGE AND ADMINISTRATION
> Initial dose: The usual starting dose of NARDIL is one tablet (15 mg) three times a day.
> Early phase treatment: Dosage should be increased to at least 60 mg per day at a fairly
> rapid pace consistent with patient tolerance. It may be necessary to increase dosage up to
> 90 mg per day to obtain sufficient MAO inhibition. Many patients do not show a clinical
> response until treatment at 60 mg has been continued for at least 4 weeks.
> Maintenance dose: After maximum benefit from NARDIL is achieved, dosage should be
> reduced slowly over several weeks. Maintenance dose may be as low as one tablet, 15
> mg, a day or every other day, and should be continued for as long as is required.
poster:ace
thread:941737
URL: http://www.dr-bob.org/babble/20100328/msgs/942302.html