Posted by conundrum on April 7, 2010, at 7:56:34
In reply to Why is Vivactil not often prescribed, posted by ihatedrugs on December 25, 2009, at 0:56:58
Damn I just read the same reviews on ask a patient and was curious about trying it. I did notice that after looking at some affinity charts it has high antimuscarinic effects.
Here are some of the review:
http://www.askapatient.com/viewrating.asp?drug=16012&name=VIVACTILHere are some tricyclic binding profiles showing high anticholinergic activity for protrityline(remember the lower the number the stronger the effect):
http://en.wikipedia.org/wiki/Tricyclic_antidepressant#Binding_profilesSimilar info in chart form:
http://i2.photobucket.com/albums/y32/tygereyes83/Muscarinic.jpg
Has anyone here had good experiences with Desipramine? I wanna try a TCA next, i'm just not sure which will be the best for me. I'd like to take one that has antagonistic effects on the 5 HT2C receptor like prozac. I think nortriptyline does that, not sure though.
Post-SSRI syndrome: iatrogenic anhedonia, memory and concentration problems, sexual dysfunction. [NOTE no sadness or anxiety, this is NOT depression!]
Current med: 100mg pristiq
Location: USA
poster:conundrum
thread:930791
URL: http://www.dr-bob.org/babble/20100406/msgs/942601.html