Posted by ed_uk2010 on April 18, 2010, at 13:55:04
In reply to Re: ultram, really... » ed_uk2010, posted by floatingbridge on April 18, 2010, at 10:52:45
>I have taken 4,000 daily of tylenol and on seperate days of ibuprofen. Neither provided noticeable relief--and alarmed my pdoc. He thinks that is above standard U.S. dose recommendations. (Well, my grandmother was from the UK.)
I believe you often give 650mg four times a day, although the maximum dose is still 1000mg four times a day. The FDA considered reducing the maximum dose to 650mg four times a day to reduce the risk of liver damage if people took multiple acetaminophen products together. The maximum dose has not been reduced to 2000mg per day.
We only have 500mg tablets here and the recommended dose is 1000mg four times a day, except for mild pain which can be treated with 500mg four times a day. Doses are given every four to six hours.
Therapeutic doses do not cause liver damage. Reduced doses are only recommended for heavy drinkers, alcoholics and patients with established liver disease.
I am aware that the FDA is concerned about the risk of liver damage due to acetaminophen overdose. They are mainly concerned about how a lot of people take more than the recommended dose of products such as Vicodin, and also that some people take multiple acetaminophen products together eg. Vicodin + Percocet + flu meds.
poster:ed_uk2010
thread:943398
URL: http://www.dr-bob.org/babble/20100416/msgs/943859.html