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Re: SSRI-induced-Sleep-Disorder induced dissociation » Pheepho

Posted by ed_uk2010 on April 24, 2010, at 11:12:44

In reply to Re: SSRI-induced-Sleep-Disorder induced dissociation, posted by Pheepho on April 24, 2010, at 10:53:45

>Thanks for the tip, that's a tricyclic, right? I think of them as pretty old-fashioned, why are they less used now?

Yes, amitriptyline is a tricyclic antidepressant. It is normally given as a single dose at night because it's quite sedating, at least to begin with. Tricyclics are effective for severe depression but they are dangerous in overdose and doctors often fear that patients may use them for suicide. Dry mouth, drowsiness and constipation are common side effects.

There are a variety of sedating antidepressants, not just amitriptyline. I thought it was worth mentioning since you do not appear to have had a good experience of newer antidepressants - especially due to the insomnia.

Mirtazapine (Remeron) is a newer antidepressant which is normally very effective for improving sleep. It generally causes fewer side effects than amitriptyline but it can cause a lot of weight gain.

 

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