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Re: Imipramine vs Desimpramine

Posted by linkadge on May 22, 2010, at 14:49:24

In reply to Re: Imipramine vs Desimpramine » linkadge, posted by Roslynn on May 22, 2010, at 11:39:04

Sorry I am using the wrong termiology.

The tertiary amines (amitriptyline, imipramine etc) are metabolized into the secondary amines nortriptyline and desipramine respectively.

Amitriptyline and imipramine are more sedative and anxiolytic. Desipramine and nortriptyline have more effect on norepinephrine and are supposedly better for low energy states.

Linkadge


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URL: http://www.dr-bob.org/babble/20100514/msgs/948332.html