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Re: need advice please » floatingbridge

Posted by SLS on May 29, 2010, at 17:29:06

In reply to need advice please, posted by floatingbridge on May 29, 2010, at 16:52:53

Hi FB.

Good luck with your new treatment.

Benzodiazepines are sometimes prescribed to help with SRI withdrawal, so the Xanax should be okay. Hopefully, the tramadol will provide enough 5-HT reuptake inhibition to ease the withdrawal from Pristiq. Will you be cross-tapering? I'm sure you know that there are reports of serotonin syndrome resulting from the combined use of tramadol with a SRI. I would probably cross-taper and monitor for signs of SS. The short half-life of tramadol (7 hours) will work in your favor should symptoms appear and you need to temporarily discontinue it.

Do you plan to replace Pristiq with another antidepressant, or is the tramadol meant to act as one?


- Scott



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