Posted by SLS on June 8, 2010, at 5:52:47
In reply to seizure threshold, tramadol, dexedrine, posted by floatingbridge on June 5, 2010, at 19:38:33
> Because of seizure risk, pdoc has withdrawn the o.k. for replacing vicodin with tramadol.
>
> Using an interaction checker, both dexedrine and lithium are contraindicated (seizures).
>
> Any advice or real world experience? I could lose the 300 lithium. Dexedrine is the only thing to date that made a real difference... That would be tough to contemplate replacing.
>
> Still working on this.
>
> Any thoughts?
>
> Thanks again.
I don't know what the "real world" risks are of combining tramadol with amphetamine. It takes a lot of tramadol to produce seizures. It has been suggested that the mechanism by which tramadol produces seizures involves the inhibition of GABA neurotransmission. I am wondering if gabapentin would be more effective than lamotrigine to prevent tramadol-induced seizures. Of course, it might not be as effective as an antidepressant adjunct.
- ScottThe measure of achievement lies not in how high the mountain,
but in how hard the climb.The measure of success lies only in how high one feels he must
climb to get there.
poster:SLS
thread:950032
URL: http://www.dr-bob.org/babble/20100604/msgs/950345.html