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Bad reaction to buspirone?

Posted by em_kath on June 28, 2010, at 19:58:03

I recently added a low dose of buspirone to 300 mg daily of bupropion. I started with 15mg (5 mg three times per day) and only made it up to about 20mg total per day before noticing that I was increasingly depressed, hopeless, and angry. I have been going through some difficult personal issues lately so it could be that I am feeling worse for outside reasons, but it seems a bit of a coincidence that during the last few weeks since starting buspirone I have felt such intense depression. I'm wondering if anybody has experienced an adverse reaction to even a low dose of buspirone? I haven't noticed any troublesome physical side effects. In my limited knowledge of the medication and how it works I don't really know what could be causing it. It could be that I just am not taking a high enough dose for it to be noticeably helpful and these feelings are unrelated. I see my pdoc tomorrow morning but I haven't decided whether or not I want to be taken off the buspirone, perhaps to increase my bupropion or add another medication. Any input would be appreciated!

On a side note, is buspirone generally associated with weight gain? I have read some conflicting information.


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poster:em_kath thread:952580
URL: http://www.dr-bob.org/babble/20100628/msgs/952580.html