Posted by g_g_g_unit on October 10, 2010, at 1:48:56
In reply to Re: Why does Parnate make some people feel so flat? » g_g_g_unit, posted by Conundrum on October 10, 2010, at 1:41:15
> IDK why. I've heard that complaint from people on askapatient.com who go on to praise the drug for lifting them out of a deep depression.
>
> I've read a couple comments on there saying that nardil cured their anhedonia, which surprised me because it increases serotonin more than parnate, which works more on dopamine. Just goes to show we don't fully understand how these drugs work and that people have different reactions to these drugs.
>
> I wonder if anyone here has found nardil helps more with anhedonia and less mood blunting.I'm not sure that you can quantifiably say that Parnate = more dopaminergic = better for anhedonia. The intensity of the start-up euphoria I experienced on Nardil far exceeded that of Parnate.
Parnate made me engage in more goal-orientated activities and improved my attention-span, but there was less a sensation of wellbeing on the drug. Parnate also made me really introverted and asocial, whereas on Nardil I wanted to be around my friends all the time.
At night, when the amphetamine effect of Parnate wore off but the therapeutic effect had yet to kick in, I would descend into the darkest, emptiest depression I've ever experienced.
I know it sounds strange that I'm reconsidering it after all that but I'm wondering if there's some initial downturn before an improvement comes about. If I fail to tolerate psychostimulants, then Parnate's my only option left really.
poster:g_g_g_unit
thread:965221
URL: http://www.dr-bob.org/babble/20101009/msgs/965226.html