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Re: Should I tell my pdoc about stablon? » Conundrum

Posted by hyperfocus on November 2, 2010, at 13:55:07

In reply to Should I tell my pdoc about stablon?, posted by Conundrum on November 1, 2010, at 22:59:47

With drugs like tianeptine you can't measure their effects using a bucket. The base action could be described as raising or lowering the levels of neurotransmitter X, but the truth is we don't have a clue what these drugs do in the brain. From what I've read Stablon and its Servier cousin Valdoxan have extremely complex mechanisms of actions hitting multiple sites in the brain that absolutely no one understands. The action of Stablon could be synergistic with any number of serotonin-enhancing meds, even though they are described as having opposite mechanisms of actions. I found tianeptine together with amitriptyline to be synergistic.

If I were you I'd keep going with the Remeron and Stablon. If you take 3 stablon at once you'll get a short dopamine rush like "everything's gonna be ok" but this isn't the true effect of the med. The real response would take probably at least one or two or three weeks to manifest. My one suggestion would be to take 1x day instead of 3x day. The recommended 3 x day dosage I think is more a logical conclusion out of the drug's short half-life, and not related to effacy. I don't notice a difference between 1 x day and 3 x day Stablon so you could save your pills.


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