Posted by Conundrum on November 7, 2010, at 14:00:00
In reply to Who has taken an NRI long-term??, posted by ggggg123 on November 7, 2010, at 13:47:22
> hi has anyone taken an NRI longterm? like Reboxetine or any of the non stimulant adhd drugs, if so did they lose their effect over time or did they provide a sustained level of treatment? Also were they effective and did you find them tolerable. Cheers
I haven't, but reboxetine is probably the one with the least side effects, and probably the least effective. It wasn't approved in the U.S. because it failed to prove effective and if you put any stock in meta analysis, reboxetine did the worst out of 12 new antidepressants, worse than all the SSRIs.
Desipramine would probably be a better bet, or nortriptyline.
From what I've read reboxetine has anti-cholinergic effects anyway, so you'd probably save money taking a generic TCA. The nice thing about reboxetine, is that you can order it online with no rx in the U.S. since it has not been approved here.
I'd go with a TCA first and if the side effects were too terrible, try reboxetine.
Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual dysfunction. )
Country:USA
Currently taking mirtazapine and tianeptine
poster:Conundrum
thread:968983
URL: http://www.dr-bob.org/babble/20101107/msgs/968985.html