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Re: New drug for depression - Long wait until approval » linkadge

Posted by SLS on November 21, 2010, at 16:58:07

In reply to Re: New drug for depression - Long wait until approval, posted by linkadge on November 21, 2010, at 11:32:35

> My personal thoughts are that purely neurotrophic agents are not going to routinely display antidepressant effects.

Yes. I have my doubts. Perhaps the drug does other things.

I sometimes think that a decrease in the volume of hippocampal tissue seen in depression is an atrophy due to disuse, as depression probably reduces afferent activity upstream that would normally stimulate the hippocampus to function and remain healthy.

It is a bit of a conundrum.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

 

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