Posted by Conundrum on December 1, 2010, at 12:13:37
In reply to Re: prozac/remeron question » Conundrum, posted by Phillipa on December 1, 2010, at 12:07:19
http://www.preskorn.com/books/ssri_s3.html
This shows the effects of different reuptake inhibitors on serotonin, norepinephrine and dopamine pumps. The smaller the number the more potent.
Fluoxetine has a fairly high number for the serotonin transporters compared to the rest of the SSRIs, but a relatively moderate number for the NE/DA reuptake pumps. So its a milder SSRI with some moderate effects on NE/DA. Citalopram has a high NE/DA number, so virtually no effect on those pumps, and a small SERT number, so its a very potent and selective serotonin reuptake inhibitor.
For infomation on fluoxetine and NE/DA release google : fluoxetine, 5 HT2C, dopamine
> To those that understand neuroreceptors it will. I just know that prozac was too stimulating for me and remeron just stopped after 30 days at 15mg as noticed nothing. I tried to google prozac with dopamine and norepenephrine last night and had no luck as curious to see how one SSRI could be what seems so different to me. Any idea what search words would bring it up? Sorry I just don't understand I guess you'd call it the science behind it? Phillipa
Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual dysfunction. )
Country:USA
Currently taking mirtazapine, tianeptine, and SAM-e
poster:Conundrum
thread:972072
URL: http://www.dr-bob.org/babble/20101117/msgs/972085.html