Posted by Christ_empowered on December 14, 2010, at 15:08:59
In reply to Quetiapine better than olanzapine?, posted by Trotter on December 14, 2010, at 0:32:50
Quetiapine may cause less weight gain than olanzapine. I think there's also less EPS across the board. It isn't "addictive" per se, but some people do have problems when they quit using it suddenly with rebound anxiety/psychosis/whatever.
I did read somewhere (Cochrane review, maybe?) that some people think that the way quetiapine binds to D2 receptors causes "receptor supersensitivty," as evidenced by the increasing doses of quetiapine required by some participants in some studies. I have read people on the internet complaining about needing ever-increasing doses of seroquel to get the job done for whatever their problem was that led to the initial prescription.
Quetiapine is lower potency than Olanzapine (think Thorazine versus perphenazine), so you'd need more in terms of dosage to get the same results and that would result in more sedation.Good luck.
poster:Christ_empowered
thread:973514
URL: http://www.dr-bob.org/babble/20101203/msgs/973549.html