Posted by sukarno on January 16, 2011, at 5:08:58
In reply to Re: Triazolobenzos don't seem to cause depression » SLS, posted by Phillipa on January 13, 2011, at 12:30:31
I've been on Xanax for years and have noticed that it too does not make me depressed like Valium or Klonopin. Klonopin definitely lowered my mood a lot worse than Valium.
I read that Xanax causes 5-HT (serotonin) release and also noradrenaline and acts on some receptor that I forgot the name of.
There was a 2007 double-blind placebo-controlled study in Japan where alprazolam (Xanax) was used as monotherapy in the treatment of major depressive disorder and it was effective.
A psychiatrist in the US told me that Xanax does have antidepressant effects but only in the higher doses and he said he wouldn't prescribe those doses. He would prescribe Klonopin with Zoloft though, but I declined.
Xanax makes me feel okay in the 4mg dosage range, but I never have developed a tolerance to the somnolence it produces. I feel somewhat sleepy and tired everyday. I suppose this could be due to lack of exercise but benzos in general are known to cause fatigue and daytime drowsiness.
Rx: alprazolam 1mg QID, famotidine 20mg BID, cetirizine 10mg BID, GNC Ultra Mega Gold vitamin supplement BID
Dx: panic disorder with agoraphobia, chronic depression, probable PTSD
poster:sukarno
thread:976654
URL: http://www.dr-bob.org/babble/20110115/msgs/976930.html