Posted by morgan miller on March 20, 2011, at 23:06:49
In reply to Re: Its not just us, posted by morgan miller on March 20, 2011, at 22:17:02
> >In light of potential antithrombotic effects of SSRIs, we hypothesized that participants taking SSRIs and other serotonergic antidepressants in the period between the initial and follow-up MRI scans would be less likely to show worsening white matter compared with participants not taking antidepressants.
>
> This was the last sentence in the introduction paragraph.OOps. This is what I meant to post..
>In this study, we did not find less frequent worsening white matter among SA users compared with nonusers of antidepressants as we hypothesized. We in fact observed a statistically insignificant effect of SA use in a direction opposite to our hypothesis. However, we did find that TCA users were more likely to experience worsening white matter compared with non-users of antidepressants. We note that a previous CHS study found no link between depression score and worsening white matter.11
It does appear that maybe TCAs are the AD's that carried the risk of white matter loss.
poster:morgan miller
thread:980618
URL: http://www.dr-bob.org/babble/20110220/msgs/980828.html