Posted by mtdewcmu on April 7, 2011, at 14:05:51
In reply to Re: Opiates and tolerance--could suboxone be worse? » floatingbridge, posted by psychobot5000 on April 7, 2011, at 10:24:39
> It seems they actually want you to take .001mg of Naltrexone, from what I read--so it's not regular LDN, rather, it's ULTRA low dose naltrexone. Apparently this is enough to do something about tolerance. Who knows if it works.
>
> I think suboxone is bonded to some other opioid antagonist, i.e. not naltrexone but nalaxone.
>
> If there's a source that recommends the higher dose--1 tenth of a miligram to a quarter, I'd like to hear about that; obviously, it's important to get the right dose.
>
> Psychbot
>
> > BB,
> >
> > My gp said that if I initiated LDN therapy while taking any norco, I'd precipitate immediate withdrawal. So your saying .1-.25mg for pain treatment maintenance?
> >
> > And suboxone, isn't that bound with naltrexone?
> >
> > Sorry. I find this so confusing. Not your answer--opoids and pain management.
> >
> >
> >
> > > To prevent opioid tolerance, take LDN with it. LDN is usually 1.5mg to 4.5mg. For your puproses, that is way too much. For opioid management we're talking ultra low dose....1/10th mg to 1/4mg. No one knows why. Theory is at that dose the receptors involved in euphoria and pain are still open and working, but the ones involved with dysphoria and tolerance are temporarily blocked. This is very new information, purely anecdotal, that I accidentally stumbled on when doing more LDN research. I came across several different forums where heroine addicts were taking ultra
> > low dose naltrexone with their heroine because they got higher, no tolerance, and no withdrawal. Can't tell you how I know, but it works the same way with cannabis.
> > >
> > > Forget suboxone. Don't need it. LDN.
> >
> >
>
>Suboxone is mixed with naloxone, which is supposed to only be active when injected. Naltrexone is active orally. Buprenorphine bonds so tightly to the opioid receptor that naloxone/naltrexone don't affect it as much, but buprenorphine itself acts as an antagonist to other opioids.
I read about LDN a few years ago and the claims that it eliminated opioid tolerance. That sounds a bit too good to be true, however, and the fact that I haven't heard much about it since tells me that it doesn't work.
poster:mtdewcmu
thread:981738
URL: http://www.dr-bob.org/babble/20110406/msgs/982192.html