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Re: Difficult Lesson Learned

Posted by mtdewcmu on April 22, 2011, at 18:20:05

In reply to Re: Difficult Lesson Learned » mtdewcmu, posted by Phillipa on April 22, 2011, at 18:05:39

> Both have a relatively short half-life not like prozac or some others. Wasn't the dose of luvox low? My pdoc always just did a switch didn't wait inbetween like with maois. I now take two SSRI's in low doses and so far have had no problems been almost a year now. Did you call your doc and ask? I wonder if luvox isn't the med for you? A paradoxical side effect? Were you on the dexadrine before. Sorry I forget. Any other factors that could have caused this reaction in you? I'm so sorry you have suffered a lot. Phillipa

The problem with Paxil is that it is a very potent inhibitor of CYP2D6. Luvox is also a potent inhibitor of a few other CYP enzymes. So I think they prevented each other from being metabolized, leading them to accumulate. The Dexedrine may have made it worse. I'm not sure whether Remeron was a net positive or negative.


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URL: http://www.dr-bob.org/babble/20110418/msgs/983544.html