Posted by SLS on August 3, 2011, at 6:47:21
In reply to Re: Day 31 of Viibryd, posted by joe schmoe on August 2, 2011, at 23:38:49
> I'm a little puzzled by this talk of miracle drugs,
Me too. No one drug heals all. However, for the one person that a specific drug does heal, it is a miracle drug.
> skipping the prescribed dosage taper,
Desperation?
> and evaluating an antidepressant after only ten days.
This frustrates me to no end when I see people draw a conclusion about the effectiveness of a drug before three weeks passes.
> Before evaluating an antidepressant I would follow the manufacturer's recommendations for dosage (unless side effects became intolerable) and give it at least month, or two months.
I don't know. I think the experience of multiple clinicians over time can yield new ways to use old drugs.
> To me Viibryd was supposed to be an ssri antidepressant
Not really. It was meant to be different. In addition to serotonin reuptake inhibition, Viibryd is a 5-HT1a partial agonist. I'm not sure, but I think the serotonin reuptake inhibition of Viibryd is less robust than the SSRIs.
> with minimal sexual or weight gain effects.
This is due to the 5-HT1a receptor partial agonism.
> No more and no less. If you never got any good effect from ssris, then Viibryd was probably nothing to get excited about.
Possibly, but clinical data on new drugs often supercedes theory.
> SSRIs do work for me for dysthymia and atypical depression. I take clonazepam for social anxiety. What I wanted from Viibryd was something like celexa but without the sexual numbing or the fatness. So far the sexual numbing seems to be absent, so I am quite happy with it. I wish my appetite was lower, but you can't have everything - and maybe that will improve over time.
I wish you luck. I hope you experience a clinical response greater than what your theory would predict.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.
poster:SLS
thread:989763
URL: http://www.dr-bob.org/babble/20110728/msgs/992667.html