Posted by Dinah on August 3, 2011, at 8:19:59
In reply to Re: Cyclothymia » Dinah, posted by SLS on August 3, 2011, at 7:02:44
http://clinicalposters.com/news/2011/0325-dysautonomia-mitochondria-pots.html
This one was interesting, but I by no means have all the symptoms.
What I was reviewing last night was the connection between migraines, IBS, vasomotor rhinitis, mood disorders, and borderline traits relating to affective instability (but not to impulsivity) and the HPA axis - in particular cortisol sensitivity.
http://www.nature.com/npp/journal/v17/n4/pdf/1380582a.pdf
http://onlinelibrary.wiley.com/doi/10.1002/ajmg.1320540412/abstract
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188657/pdf/jpn00059-0041.pdf
http://www.ncbi.nlm.nih.gov/pubmed/12062878
I think there were other issues I ran across also, though I can't recall them offhand. I originally ran across the idea while researching a very embarrassing manifestation of vasomotor rhinitis. :) I think it's more a question of stress intolerance and sensitivity rather than the more severe dysautonomia. Of course, there's always the question of chicken and egg. Was it caused by long term stress or does it cause an intolerance to stress.
I suppose it's my involvement with dogs that predisposes me to believe there must be an underlying biological component to this.
And that this somehow should be reflected in the DSM. It just irritates me no end that there is clearly this population of people who not only have emotional lability, but often also have physical issues that have been linked to problems in the HPA axis, and yet it's ignored in the bible of the profession.
Granted, I may like this theory in part because it validates my own observations. I also liked the breakdown of borderline personality into two biological groups of characteristics. This explains why the disorder fits so completely in some ways, but not well at all in others. It also explains my very good reaction to Risperdal. There were a couple of studies showing that some AP's but not all AP's were helpful with regard to cortisol sensitivity. Risperdal is helpful.
So maybe I just like the theory because it seems to fit all the pieces for me, and also is in line with my own thoughts on the issue.
I was sorry to hear of what's going on with your friends, Scott. It is truly a difficult situation, and surely you must take that into account when you are thinking about your own health. It doesn't necessarily mean that your medications aren't working as well, just that you're under a strain.
poster:Dinah
thread:992265
URL: http://www.dr-bob.org/babble/20110728/msgs/992671.html