Posted by linkadge on August 27, 2011, at 9:41:38
In reply to How do sex hormones affect the CNS/brain?, posted by zonked on August 26, 2011, at 21:18:41
I don't know for testosterone specifically, but hormones interact with neurotransmitters just like psychotropic drugs do.
For instance, thyroid inhibits monoamine oxidase as well as the norepinephrine and dopamine transporters. Estrogen is a monoamine oxidase inhibitor. DHEA acts as a sigma agonist as well as inhibiting monoamine oxidase. Progesterone enahances gaba activity (at gaba-a receptors) while estrogen is a gaba antagonist. Many of the hormones also promote neurotransmitter release.
Testosterone has some effect on dopamine, but I am not sure about the mechanism of action.
poster:linkadge
thread:994958
URL: http://www.dr-bob.org/babble/20110822/msgs/994991.html