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Re: Nardil anhedonia, need TCA? SLS? » Conundrum

Posted by SLS on September 6, 2011, at 10:36:22

In reply to Nardil anhedonia, need TCA? SLS?, posted by Conundrum on September 5, 2011, at 21:09:43

> It seems that since I've started Nardil I've been more lethargic and lazy than normal. Usually I just want to sleep or do nothing. I find less interest in things that always helped my anhedonia a little like video games.
>
> I am wondering if things improve with a higher dose, or perhaps I should consider asking my pdoc on wednesday for nortriptyline, desipramine, or protriptyline to help with the anhedonia. I know he likes the stim + MAOI combo, but I have never had positive or pleasant experiences from stimulants.

The first time I added desipramine to Parnate, I experienced a robust improvement that lasted for several months. It was as if the Parnate helped to stabilize the tricyclic response. Otherwise, desipramine poops-out on me within three days of the appearance of an antidepressant response.

Regarding anhedonia, TCAs can do a good job. No theory here. It is simply an empirical observation. Theory is often a fruitless way to attack depressive illness.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

 

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