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Re: BDNF connection? » zonked

Posted by SLS on September 20, 2011, at 22:15:24

In reply to Re: BDNF connection? » SLS, posted by zonked on September 20, 2011, at 21:36:30

>
> > Which drugs made you feel dramatically worse?
> >
> >
> > - Scott
>
> May I?
>
> Effexor XR (extreme anxiety/akathisia like feeling), Wellbutrin SR and XL (extreme anxiety and quickness to anger), nortriptyline (same as Wellbutrin), selegeline (depression somewhat relieved but anxiety very Wellbutrin-like.)
>
> Meds that worked, but then pooped out: Zoloft (yay! best ever.), Nardil (seems to work in combination with testosterone but never as well as the first two times), Parnate (dose had to go so high over time as to provoke unacceptable hypomania, where the response became hypomania or nothing.)
>
> My doctor once mentioned "super-dosing" SSRIs to regain response. One other professional mentioned this: a psychiatric NP I met who has bipolar disorder herself. Should I not regain the response I had recently after re-adding Testim, I dunno what I'm gonna do.
>
> I will look to see what you have to say about Viibryd, that's for sure.
>
> Hope I didn't offensively hijack the thread folks..
>
> -z
>


Intolerant of NE drugs, perhaps? Are there any drugs that you responded well to that were NE reuptake inhibitors? How about NE alpha-2 antagonists like Remeron > 45mg or Buspar (via metabolite 1PP).

How about trimipramine (Surmontil)? Nefazodone? I agree with you that Viibryd might be worth a try.

My doctor would love for a drug to trigger mania in me. He would simply add anti-manics and retain the antidepressants. Depakote and Zyprexa squash my manic episodes within 12 hours of the first dose.

How about adding guanfacine when NE drugs agitate you? (wild guess). You might even want to try it regardless.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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