Posted by Bob on September 30, 2011, at 1:42:58
In reply to Re: Provigil and Nuvigil - Long-term effectiveness?, posted by creepy on September 30, 2011, at 1:02:30
> Seems like every drug that works on dopamine suffers from the same thing. an initial boost followed by eventual poop-out.
> What is it about dopamine in the brain that seems to be in a feedback loop, versus serotonin? You dont see nearly as many SSRIs pooping out so quickly.
> If the brain re-adjusts to higher levels of a neurotransmitter, why does tinkering with serotonin work so well for so many?
> If anyone has a link to info on this Id be interested to check it out.
>
Yes, the brain's adaptation to our therapeutic efforts seem to quite a foil to efforts to treat mental illness in certain cases. I wish a way to "reset" the brain could be found.
poster:Bob
thread:998262
URL: http://www.dr-bob.org/babble/20110925/msgs/998336.html