Posted by SLS on October 19, 2011, at 13:05:11
In reply to Re: Viibrid Treatment » SLS, posted by europerep on October 19, 2011, at 8:39:29
> Hello Scott,
>
> to be honest, what I don't understand is why you don't consider participating in clinical trials for more novel agents.I did a lot of that in the 80s and 90s. I am not too keen on discontinuing everything I am currently taking in order to participate in a clinical trial. I would certainly try something new were there to be compelling results already established. The other thing to consider is that most of these investigations exclude me from consideration because of my bipolar history.
> There are a bunch of trials going on in the US for ketamine in TRD, either intravenous or intranasal.
I'll look into that. I know there is at least one compound being developed that works like ketamine, but without the euphoria. I don't remember the name of it.
> If you profited from it, you could still get it from the black market if the doctors refused to give it to you on a regular basis.
I had thought of that, but I wouldn't know where to get it. Unfortunately, the window for ketamine is very, very narrow. It might be a difficult drug to dose properly.
> If you're afraid of legal trouble, try methoxetamine, which is an unregulated substance somewhat similar to ketamine.
Thanks for the lead. I had never heard of it. I see on Wiki that methoxetamine is also a dopamine reuptake inhibitor. Just what the doctor ordered.
> I know you are very patient, but I'm wondering whether you may actually be *too* patient.
I certainly wish that I hadn't spent this past year taking Nardil. I felt encouraged to do so based upon the occurrence of a second wave of improvements that occurred last December.
> After trying out I-don't-know-how-many drugs that act on 5HT/NE/DA, I would conclude that it's time to look elsewhere. Buprenorphine may be worth trying as well.
The last time I asked my doctor about buprenorphine, he refused to work with it.
> Just my thoughts...
Good ones. Thanks.
I will definitely keep them in mind. I think you are right about me having to look elsewhere for help.
I would like to have seen the triple reuptake inhibitors rise up through Phase III trials. They seem to have been dropped.
http://www.neurotransmitter.net/newdrugs.html
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:994620
URL: http://www.dr-bob.org/babble/20111016/msgs/1000215.html