Posted by ed_uk2010 on November 13, 2011, at 15:48:41
In reply to Re: To Christ Empowered, posted by Christ_empowered on November 13, 2011, at 9:53:58
>I'm sorry your shrink said no, but it's not as if you're missing out on too much.
Efficacy of asenapine (Sycrest, Saphris) does not look too impressive. It does not seem to be as effective as olanzapine (Zyprexa), and the differences from placebo were not that great.
From the European Medicines Agency website.....
'Sycrest was effective at treating manic episodes in patients with bipolar disorder. In the first short-term study, the reductions in Y-MRS score after three weeks were 11.5 and 14.6 points for Sycrest and olanzapine, respectively, compared with 7.8 points for placebo. The reductions for the second short-term study were 10.8 and 12.6 points for Sycrest and olanzapine, respectively, and 5.5 for placebo.
In the first long-term study, a reduction in Y-MRS score of 12.9 was seen in patients taking Sycrest compared with 16.2 in patients taking olanzapine. In the second long-term study, the reductions in Y‑MRS score were 10.3 and 7.9 for Sycrest and placebo, respectively, after three weeks and 12.7 and 9.3 after 12 weeks.
The studies on schizophrenia were not considered to have shown sufficient evidence of the effectiveness in treating this disease.'
poster:ed_uk2010
thread:1002448
URL: http://www.dr-bob.org/babble/20111110/msgs/1002481.html