Posted by SLS on November 28, 2011, at 7:10:29
In reply to Re: Valproate - Clonazepam interaction?!, posted by SLS on November 28, 2011, at 6:53:50
> > I read in a good book that Valproate inhibits the elimination of Clonzapam. Unfortunately there was no source in the book about this info. Did you know that and have you some further info?
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> http://www.ncbi.nlm.nih.gov/pubmed/14651674
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> "Concomitant administration of clonazepam and valproic acid resulted in a 14% increase in clonazepam clearance, and a 17.9% decrease in valproic acid clearance."
These guys may have it 180° backwards.
----------------------------------------------I found this:
http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZGYZ805.001.htm
"The results showed that sodium valproate increased the concentration of clonazepam at every time point.
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- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1003741
URL: http://www.dr-bob.org/babble/20111120/msgs/1003754.html