Posted by bleauberry on December 18, 2011, at 7:59:26
In reply to Low-dose naltrexone, anyone tried it for CFS/FM?, posted by creepy on December 13, 2011, at 13:03:03
LDN is a no brainer for anyone with any sort of chronic disease or psychiatric symptoms or both. It seems especially well suited for the mystery diseases....lyme, cfs, ms, fibro, etc. More often than not it ends up not being a cure, but is helpful enough in a way that people want to stay with it because it improves life quality in a meaningful way. They commonly relapse back to where they started when they stop it.
As with everything, mileage varies. New discoveries show that much tinier doses are effective for some people, and necessary since many of these mystery disease people have exquisite sensitivities and need exquisitely small doses. LDN is usually 1.5mg to 4.5mg but now some people are finding even just 1/10th of that is good. It has also been seen that some people do better with daytime dosing rather than bedtime dosing. So we have seen some new things since LDn first cam out.
I've tried it several times and I guess I am one of the rare people that doesn't do well with ldn. Makes me much more depressed and very high anxiety, which is very unusual for that med at those doses. I think the longest I stayed with it was about 3 weeks. Have tried doses from 0 .1mg to 3mg and various dosing times.
The immune system is tied into every other system in our body more than we know, including the nervous system where psychiatric or neuromuscular symptoms originate. It is my theory that many if not most CFS/FM patients actually have an infection of some sort....bacterial as in lyme or lyme-like, or viral, sometimes fungal such as candida. Assume for a moment that is true, then anything that is going to modulate the immune system....that is, turn it up where it is weak, and turn it down where it is too strong (autoimmune) jas the potential to be helpful. LDN falls into that class. Antibiotic herbs also. My Lyme doctor was a pain/fatigue specialist before that, until he discovered by accident that his patients got better on antibiotics than they did on his routinie pain/fatigue meds. LDN is sort of like that.
Along those same lines, you HAVE to take a look at rhodiola rosea if you haven't already.
poster:bleauberry
thread:1004876
URL: http://www.dr-bob.org/babble/20111208/msgs/1005166.html