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Re: Emsam poop out, a new maoi?

Posted by williamockham on January 2, 2012, at 11:07:12

In reply to Emsam poop out, a new maoi?, posted by Erewhonian on December 26, 2011, at 13:39:35

I started keeping the patches on a few days...up to 3 at a time (the 9mg has 30mg in the patch, so if absorption is linear, basically 3 9mg patches gives 9 + 6 + 4 = 19mg/day.) Definitely felt a difference vs 9 or 12, although still not nearly as much as Nardil.

No one (AFAIK) has done tyramine pressor tests on higher Emsam doses, so it might make the diet mandatory...maybe to a lesser extent since transdermal leaves gut MAO-A pretty much intact (tested in rats up to absurd doses). If you gotta really watch the diet, and deal with multiple patches in various states of falling off, kinda defeats the benefits of Emsam vs Parnate/Marplan.

Best of luck convincing the pdoc. I've certainly had my share of shy ones with MAOIs..


Nardil 90, Lamictal 175, Seroquel 75


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poster:williamockham thread:1005595
URL: http://www.dr-bob.org/babble/20111226/msgs/1006149.html