Posted by Tony P on January 3, 2012, at 22:13:15
In reply to Re: Antidepressants, Talk Theraphy, Placebos All Same » jhj, posted by SLS on December 29, 2011, at 5:34:28
The results don't surprise me given the many weaknesses in the design. As I think someone else commented, the results could also be interpreted as "ANY _single_ treatment works for about 1/3 of depressed patients", which agrees with most other studies I have seen.
My biggest beef with small but over-generalized studies like this is that they take no account of individual responses to ADs, far worse in this case because only 2 ADs were considered.
As an example, survey papers comparing SNRIs generally conclude that Cymbalta is inferior to Effexor overall (as a result, my drug plan covers Effexor but not Cymbalta. Grrr.). However, for me Effexor is intolerable because of side-effects, Cymbalta is more effective than nearly every AD I have tried, and has almost zero S/E. My pdoc has also found Cymbalta effective & low S/E with many of his patients. Where am I in these collective averages?
poster:Tony P
thread:1005682
URL: http://www.dr-bob.org/babble/20111226/msgs/1006272.html