Posted by SLS on February 7, 2012, at 6:01:24
In reply to Re: update » SLS, posted by g_g_g_unit on February 7, 2012, at 5:21:27
> > > ugh. I'm feeling so depressed and flat and apathetic this evening. this is bringing back bad memories of my last trial. I'm wondering if I should just increase the dose as fast as possible.
> >
> > You might be "using up" your neurotransmitter stores as you experience a stimulant effect without first having established MAO inhibition.
>
> Yes, the crash is very similar to that which I experience on Dexedrine. Does Parnate release DA/NE at lower doses?Whatever it does, it probably does it at all dosages. I don't know what the current thought is regarding the mechanisms involved with the stimulant-like effects of Parnate. After all of these years, there are still people searching for an amphetamine metabolite.
> Would MAO inhibition help bolster against this
effect?If one were to entertain the hastily-drafted idea that I proposed, the answer would be yes. I think you should look forward to things getting better.
> I think I remember the 'crash' improving after raising to 30mg last time.
Good guess on my part, perhaps?
> Thanks. I think I'm just scared right now.
I know. I would be, too. You desperately need something to work, and you don't want there to be any complicating negative side-effects with Parnate.
> There's quite a few reports of people feeling very flat/apathetic on Parnate.
I cannot report that.
> I was hoping it might relieve my apathy and anhedonia,
Parnate does improve these things for me, although I find Nardil to do this more so.
> though last time at 30-40mg I recall feeling quite flat.
That is interesting. However, if you had not achieved sufficient MAO inhibition, you cannot come to any conclusions.
> The problem is I was worried my psychiatrist would grow weary of me if he'd known I had already trialed both MAOI's. This is probably an unreasonable fear, but regardless, I know lower doses don't help, so would like to reach 60mg as soon as possible;Go for it. Don't titrate too fast, though. You don't want to get turned-off to Parnate because of the side-effects it might provoke.
> I hope I don't get stuck spending weeks titrating.
That should not be necessary. You can probably reach 60 mg by the end of week 3. I don't think that this is particularly aggressive.
> Serves me right though I suppose.
I don't know what you are referring to, but I bet that this is the depression talking.
Good luck.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1009314
URL: http://www.dr-bob.org/babble/20120202/msgs/1009545.html