Posted by novelagent on February 25, 2012, at 3:10:31
In reply to Re: ketamine can cause psychosis...does it??, posted by roversreturn on February 20, 2012, at 20:28:53
First of all, no. no. no.pot is also "reversible." I don't think you quite grasp the concept of a compounding circumstance, in which a temporary psychosis triggers schizophrenia-- an insult, or trauma, of sorts, to the brain.
Would you say the flu can't kill someone with AIDS because the flu only lasts for a week or less in a healthy adult? No. Just because it's "reversible" in healthy subjects does not mean it is also therefore reversible in people who take it who are predisposed to schizophrenia and have schizophrenia.
Moreover, your argument about ketamine "reversing" schizophrenia is just baseless and made up.
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> Ok great, you may be right that this could be a no no for people suffering from schiz, but i would argue they may get better when the drug leaves their system (as in depression).
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> The article implies that ketamine's temporary activity on glutamte in brain during the time the drug is taken means that even 'normal' people have temporary symptoms of schizophrenia, this can be attentuated by lamotrigine apparently, once the two hours or so has passed one would expect to feel 'normal'. This is when the antidepressant effect appears to kick in.
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> "The psychomimetic effects of ketamine are transitional, reversible and influenced by time, dose and administration conditions". Therefore one would not expect ketamine to attribute to onset of schizophrenia, in the way that say, cannabis had been hypothesised.
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> Thanks
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> Rover
poster:novelagent
thread:1010025
URL: http://www.dr-bob.org/babble/20120221/msgs/1011487.html