Posted by displaced9 on April 18, 2012, at 19:38:27
Hi all,
I'm hoping someone can offer advice. I have been taking Effexor XR 225mg w/ Wellbutrin XL 300mg both in the AM for dysthymia and anxiety for awhile but have had trouble sleeping since I stopped taking Remeron (Mirtazapine) at bedtime about 4 months ago due to massive weight gain and irritability. My pdoc tried me on Geodon 40mg w/ food an hour so befor bed for sleep. The first night , this knocked me out. Subsequent nights, not so much, then it started having the opposite effect. I felt very "sped up" after taking it at night and it made it even more difficult to sleep. I contacted him and let him know and he advised me to try taking (2) 40mg capsules to make 80mg, as the 40mg was to test tolerability as 40mg is plenty for some patients but the 40mg can cause the keyed up feeling in others. He reminded me to take it with food. I tried this for several nights. Again, knocked me out first 2 nights. It's been about 1.5 weeks at 80mg, and the past 4 days have absolutely miserable. I have had trouble sleeping, so I take melatonin and unisom to sleep, but the following day I feel SO keyed up, sped up , etc like I am on amphetamines. The same feelings I got many years ago when I used methamphetamine once, and when I was misdiagnosed as ADHD and put on Adderall for a few days. Restless, sweating and just can't calm down. I have to take 3-4 mg of klonopin just to be decently at ease, mind you, i'm not anxious.. just restless.
I cut back my Effexor dosage to 75mg and today didn't take the Wellbutrin at all, as I read that Geodon can potentiate CNS stimulating effects of drugs, but none of this helping so far. Do I need to go to a higher dose on the Geodon? The Effexor + WB + Geodon (prior to the keyed up feeling) had me feeling really good. Probably the best ever. Will 120 mg get me to that nice even plateau again?
Many thanks all!
Jason
poster:displaced9
thread:1015909
URL: http://www.dr-bob.org/babble/20120411/msgs/1015909.html