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Re: cymbalta and another SNRI » b2chica

Posted by SLS on June 12, 2012, at 19:15:31

In reply to cymbalta and another SNRI, posted by b2chica on June 12, 2012, at 15:40:27

> i'm on
> pristiq
> (adderall, perphenazine, and gabapentin(prn) xanax(prn))
>
> could i try adding on cymbalta even though its another snri? i typically have bad results with ssri so please dont suggest.
> and yes tried pristiq at 100 nothing.

What is your rationale for choosing to combine these two drugs?

> please tell me if this would be a possibility?

I would consider adding either Wellbutrin or nortriptyline first. Maybe Remeron would also help. I cannot guarantee that adding Cymbalta would not work, but I think the other drugs may be more complementary with regard to mechanisms of action. That being said, Pristiq and Cymbalta are, indeed, different drugs, despite their having overlapping properties. Perhaps combining them would help. There may be important properties of these drugs that do not overlap. The obvious concern regarding the combination of two drugs that are serotonin reuptake inhibitors is that of precipitating serotonin syndrome.

> i'm afraid he'll laugh off my symptoms, or tell me their all in my head...all psychological.

> i dont want to live like this. pretending forever. i cant feel anything. i laugh when i'm supposed to, i smile when i'm supposed to, but i feel nothing. i'm a void.

It is obvious to me that you are a hard-worker and unwilling to capitulate at this point. However, your affect is flat. You might suffer from anhedonia. I don't see dysphoria in your description. Being void of feelings can be a psychological reaction to avoid the pain of dealing with emotional issues. However, it seems more likely to me that the presence of anhedonia argues for your having an illness with a more prominent biological component.

Which atypical antipsychotics have you tried so far? What were the results?


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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