Posted by brynb on August 13, 2012, at 9:06:43
In reply to Re: lyrica - how does it work » rjlockhart37, posted by SLS on August 13, 2012, at 6:25:30
> > similar to nuerontin.....well its its sister drug...anyways, it reduces firing by using the GABA receptors but it doesnt do the benzo thing...its unique how it works because of pain relief and mood aspects, it has been known to improve mood, but mainly its used for anxiety when benzos are not considered.
>
Rj, the above is true to an extent. It doesn't really work directly on GABA, otherwise its effects would be very similar to benzos, barbiturates and alcohol.
> I don't think it is yet clear how Neurontin works. I think it depends on which circuits are being examined. It hurts my brain whenever I attempt to figure it out.
>
> I doubt Neurontin modulates GABA receptors directly.Scott, this is true. It seems "they" aren't too clear on how it works in general. The stuff was initially marketed by Pfizer as snake oil, touted as helping practically every condition under the sun. And they did find themselves in hot water over it.
The idea that the drug's mechanism isn't clear seems supported by those who have taken it; it helps mood/it doesn't help mood; it helps anxiety/it causes anxiety and so on. And although it's used as a mood stabilizer, I became manic on it.
-b
poster:brynb
thread:1023132
URL: http://www.dr-bob.org/babble/20120803/msgs/1023179.html