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Re: A call to my White Knights Jono and SLS for advice » ChicagoKat

Posted by SLS on October 5, 2012, at 13:33:01

In reply to Re: A call to my White Knights Jono and SLS for advice » SLS, posted by ChicagoKat on October 5, 2012, at 11:44:35

> Scott...I just want to make sure, if I took 150mg/day of elavil with 45mg/day of nardil, that it would be safe?

Been there, done that...

It was safe enough for me. Hopefully, it will be for you, too.

The only thing I can think of that would be unsafe about this combination is the possibility that it would precipitate serotonin syndrome. You should get familiar with its signs and symptoms, just in case. I really don't see it happening, though.

Because of its anti-cholinergic, central pro-adrenergic, and peripheral NE alpha-1 antagonism, adding amitriptyline to Nardil might produce some problematic hypotension, tachycardia, and urinary retention that will need to be remediated pharmacologically. These things are less of a problem when the dosage of Nardil is kept below 60 mg/day. Let's see what happens and take it one step at a time.

Good luck!


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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