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Re: Ritalin while on an maoi » SLS

Posted by ChicagoKat on October 7, 2012, at 12:00:17

In reply to Re: Ritalin while on an maoi » ChicagoKat, posted by SLS on October 7, 2012, at 7:06:56

> Why a stimulant?
> Why Ritalin?
>
> Nardil + Ritalin?
>
> Ritalin does not inhibit the reuptake of serotonin. It does not bind to the transporter. However, there is a study of rats reporting that adding Ritalin to Celexa can produce a greater increase in serotonin levels in the hippocampus compared to Celexa alone. No such effect was reported in the cortex.
>
> http://www.sciencedirect.com/science/article/pii/S0924977X07000508
>
> I don't know about Nardil, but I have added Ritalin to Parnate + desipramine. In fact, some doctors have done this as a way to remedy Parnate-induced hypotension. I have also added Dexedrine and Adderall to Parnate. I cannot remember adding a stimulant to Nardil.
>
> I can't find on Medline/Pubmed an abstract regarding Nardil and Ritalin used in combination. There is only a letter reporting a case study, but without the abstract.
>
> http://www.ncbi.nlm.nih.gov/pubmed/14970373
>
> If it were me, I would try amphetamine first. However, I would not exclude Ritalin from consideration.
>
>
> - Scott
>
>
>
>

ps I looked it up. Half-life of IR Ritalin is 2-4hrs. As far as IR Adderall goes, half-life of d-amphetamine is 10hrs, for l-amphetamine it is 13hrs. It is Ritalin's considerably shorter half-life and thus doa that makes me prefer it, in case anything should go awry.
Kat


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