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Re: Anxiety and dose » jono_in_adelaide

Posted by SLS on December 18, 2012, at 0:29:51

In reply to Re: Anxiety and dose, posted by jono_in_adelaide on December 17, 2012, at 21:28:59

> Could you cousider a trial of Parnate in higher doese, with or without nortriptyline for antidepressant effect, and a benzo to counter the anxiety?

I guess it's possible that higher dosages of Parnate will reduce anxiety if the antidepressant response is robust enough. However, I am less sure of this when lower dosages of Parnate are actually anxiogenic. It might make sense to try increasing the dose anyway since GGG is already taking the drug. I do have a small amount of concern about provoking spontaneous hypertensive reactions with Parnate. I would have my blood pressure taken at least once. Interestingly, in the old days, measuring BP upon orthostatic challenge was one method by which doctors would estimate MAO inhibition. Sufficient therapeutic inhibition was assumed if, upon standing, BP fell by at least 10%.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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