B. infantis reduces inflammation + depression

Posted by Trotter on December 22, 2012, at 18:24:57

In reply to Re: Translocation of bacteria -) depression, posted by Trotter on December 22, 2012, at 14:43:57

Probiotics, which also seem to have anti-inflammatory effects, have had antidepressant and anxiolytic actions in animal studies. The human studies are very few and far between. From my own research, the most promising strain is Bifidobacterium infantis 35624 (sold as Align).
Here are some quotes and sources:
However, there was a significant attenuation of IFN-gamma, TNF-alpha and IL-6 cytokines following mitogen stimulation (p<0.05) in probiotic-treated rats relative to controls.
http://www.ncbi.nlm.nih.gov/pubmed/18456279
In a study announced on May 21, 2007, at the 38th annual Digestive Disease Week conference, a naturally occurring bacteria (Bifidobacterium infantis 35624) showed anti-inflammatory properties in a mouse model of arthritis.
This bacteria has previously been shown to modulate the inflammatory response in a clinical trial in irritable bowel syndrome. Data released from this study indicate that the probiotic may have anti-inflammatory action outside of the digestive tract.
http://www.arthritis.org/research/funded-research/research-update/journal-summaries/probiotic-anti-inflammatory/
In this study of rats given B. infantis, there was a reduction in pro-inflammatory cytokines.
http://www.ncbi.nlm.nih.gov/pubmed/18456279
In this study, B. infantis lowered pro-inflammatory cytokines and protected rats from depression induced from maternal separation.
http://www.ncbi.nlm.nih.gov/pubmed/20696216
Other probiotic bacteria to show anti-inflammatory, antidepressant or anxiolytic action include Bifidobacterium longum and Lactobacillus rhamnosus.

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High fat diet -) inflammation -) depression Trotter 12/19/12
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Re: High fat diet -) inflammation -) depression » Trotter SLS 12/21/12
Re: High fat diet -) inflammation -) depression » Trotter SLS 12/22/12
Re: High fat diet -) inflammation -) depression jono_in_adelaide 12/22/12
Re: High fat diet -) inflammation -) depression » jono_in_adelaide SLS 12/22/12
Re: High fat diet -) inflammation -) depression Trotter 12/22/12
Re: High fat diet -) inflammation -) depression Trotter 12/22/12
Re: High fat diet -) inflammation -) depression jono_in_adelaide 12/22/12
Re: High fat diet -) inflammation -) depression » Trotter SLS 12/22/12
Re: High fat diet -) inflammation -) depression Phillipa 12/22/12
Re: High fat diet -) inflammation -) depression Trotter 12/22/12
Translocation of bacteria -) depression Trotter 12/22/12
Re: Translocation of bacteria -) depression Trotter 12/22/12
B. infantis reduces inflammation + depression Trotter 12/22/12
Re: B. infantis reduces inflammation + depression » Trotter SLS 12/22/12
Re: B. infantis reduces inflammation + depression » SLS Trotter 12/22/12
Re: B. infantis reduces inflammation + depression » Trotter SLS 12/22/12
Re: B. infantis reduces inflammation + depression » Trotter SLS 12/23/12
Re: B. infantis reduces inflammation + depression Trotter 12/23/12
Re: B. infantis reduces inflammation + depression Trotter 12/23/12
Re: B. infantis reduces inflammation + depression » Trotter SLS 12/23/12
Re: B. infantis reduces inflammation + depression » SLS Trotter 12/23/12
Re: High fat diet -) inflammation -) depression larryhoover 12/25/12
Re: High fat diet -) inflammation -) depression larryhoover 12/25/12
Re: High fat diet -) inflammation -) depression larryhoover 12/25/12
Re: High fat diet -) inflammation -) depression » larryhoover Trotter 12/26/12
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Re: Bifidobacteria reduce depression (nm) » Trotter Rosscoe 4/1/15

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