Posted by gilmourr on January 16, 2013, at 12:08:00
In reply to Re: Gillmore » gilmourr, posted by AlexCanada on January 16, 2013, at 7:02:53
> > > Hi mate
> > >
> > > before you consider undergoing ECT, would you consider posting a list of which drugs you've tried, and what effect each had on your symptoms
> > >
> > > A few of us (especialy Mr SLS) might have some ideas that could help without going through ECT, which while it can be life saving in severe melancholic depression, could hardly be described as a fun experience
> >
> > More than glad to.
> >
> > Paxil - nothing @ 30 mg, 8 weeks
> >
> > Prozac - Side effect sh*t storm, vomiting, no go here
> >
> > Cipralex - 40% reduction in depression @ 20 mg, LOADS of insomnia, slept like 1 hour every 2 days. (8 weeks)
> >
> > Zoloft - No side effects or just mild GI symptoms, seemed to work on depression and anxiety as well as cipralex (best SSRI)
> > (8-9 weeks)
> >
> > Nardil - F*ck*ng godly. This was almost remission, but I went to 60 mg and had bad mood swings so I came off it. When I went on 45 mg after 14 days being off it, it didn't work as well and I had more side effects. So this MAY be an option, I just think I need a break from it. (Also it gave me shivers and cold intolerance, if there's a way to get rid of this side effect it'd be PERFECT). (10-12 weeks)
> >
> > Remeron - Slept 14-16 hours a day, great AD, nothing for anxiety, massive acne out breaks. Overall its good but I felt like a retard on this as I couldn't think. 8 weeks at 7.5 mg (I know, 7.5 mg...)
> >
> > Effexor XR - High BP 165/125 and rising, stabbing chest pains, quit after 13 days. The chest pain was really bad. 75 mg
> >
> > Celexa - Awful sexual dysfunction, even worse insomnia than cipralex. I wanted to go to sleep so badly but just couldn't. 20-30 mg
> >
> > Parnate - Had a great AD response at 30 mg for 2 days, then it crashed. Then was hypothermic for 18 days straight. Freezing my *ss of so badly.
> >
> > Lamictal - It was looking promising, but I had breathing issues on it, I could hardly breathe. It was 24/7 and did not seem tied to anxiety.
> >
> >
> > I want to go back on Nardil because it's godly, I just am waiting 2 months to see if the effect comes back. But I think it's too much norepinephrine. Though TWICE at 45 mg I had only constipation and it was working well. For some reason the 3rd time I tried Nardil it gave me all my side effects of 60 mg (even though I was on 45 mg) which I was like wtf. So I'd probably start at 30 mg this time and see if that's enough. I've never tried 30 mg.
> >
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> Have you tried lower doses of some of these meds? Nardil and Parnate in particular. Parnate was wonderful for me below 30mg regardless of what the 'studies' show. Going up to 30mg was pretty lousy.
>
> Nardil is a miracle for many. You may want to strongly consider giving a particular dose more than a few weeks otherwise you may be dealing with withdrawal or other such issues from the previous dose. And you may want to start lower than moderate and high doses when it comes to meds in general.
>
> With strong side effects it may be possible that you may have some med sensitivity. For some people low doses work wonders because even 20mg of Parnate is capable of having profound incredible effects in certain individuals. I was one such case.
>
> Starting modest and increasing the dose if needed is better in most regards than starting off at a high dose.
>
> Nardil 45-60mg could be terrible for someone while 30mg could be the magic number. it's better to try such options first before donating your brain to science. Old studies from the stone age don't tell the whole story of ECT.Have not tried a lower dose of Parnate. Maybe I'll give that a shot one time down the road.
And for Nardil since my 1st trial I know to give each dose 6-8 weeks because like you said, it is really about finding that magic number.
Nardil may work again. I'm going to try magnetic seizure therapy, it's basically magnets used to induce a seizure and there seems to be very very minimal cognitive damage, if any. I'm looking through all the info I can find, but check it out and tell me if you agree.
I was thinking.. do MST and then add Nardil @ 15-30 mg.
Basically I will have been off Nardil for 2 months, so the resistance should be gone. Hopefully.BTW, what is your opinion of neurontin?
poster:gilmourr
thread:1035478
URL: http://www.dr-bob.org/babble/20130112/msgs/1035626.html