Posted by cellular on January 24, 2013, at 10:07:42
In reply to Re: More evidence of inflammation and depression. » SLS, posted by brynb on January 2, 2013, at 11:58:26
> Scott,
>
> It makes a lot of sense. I don't know about other antibiotics, but I've been sick all month, and I've been on Keflex (cephalexin) for a week and a half and I think it's been helping this recent depressive period.
>
> Thanks for the info.
>
> bInteresting observation.
I had similar experiences with an antiviral, in my case acyclovir -- one time when I was treated with it for an outbreak of shingles and the second time about two years later when I felt the same tingling skin sensations that preceded my first shingle outbreak and asked the doc for the same med as a prophylactic measure.
In both cases I felt a significant improvement of my depressive condition -- not as powerful as when taking the anti-inflammatory glucocorticoid prednisolone but strong enough that I wished it were a med that I could take off-label ad libitum.
I digress a bit now, but interestingly there are also indications that the use of the NSAID ibuprofen may delay or even prevent the onset of Alzheimer's disease which according to some medical professionals is caused by inflammation within the brain:
Warding off Alzheimer's with Ibuprofen
http://www.npr.org/templates/story/story.php?storyId=91381068
"There is no cure for Alzheimer's disease, but there may be a way to prevent it with common ibuprofen. An enormous study of 50,000 patients shows that certain anti-inflammatory drugs are probably helpful in delaying or preventing Alzheimer's."
Also, antihistamines combat certain inflammation and there are several tricyclic antidepressants that have more or less pronounced antihistaminic effects which may aid in relieving some patients' depressive condition.
I vividly remember the nasty allergic reactions I had during a wash-out period of the tricyclic doxepin. Back then I couldn't figure why I experienced those unusual allergic reactions but later I stumbled upon information of doxepin's action as a histamine H1-receptor antagonist.cellular
poster:cellular
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URL: http://www.dr-bob.org/babble/20130124/msgs/1036337.html