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Re: Zoloft Anxiety at first? » CamW

Posted by SLS on February 18, 2013, at 21:05:13

In reply to Re: Zoloft Anxiety at first? » PrettyLady, posted by CamW on February 18, 2013, at 20:20:56

> Yes, increased anxiety is a start-up side effect of all the SSRIs. Your body just has to adjust to the increase in availability of serotonin, by down regulating some of the extra post-synaptic serotonergic receptors.

That's a very concise explanation. Very nice.

> People who take SSRIs for panic disorder almost always experience an increase in panic attacks when starting the SSRI. This is why many doctors give a week or two of benzodiazepines to help decrease the increased anxiety. After the couple of weeks, the incidence of panic attacks significantly decrease & even stop.

Which drugs do you feel are most effective for panic disorder? In another era, imipramine was considered to be the reference drug for this indication. Would Effexor be more effective than Zoloft? Is Paxil the most efficacious SSRI for panic disorder? How do you rate Lexapro for PD?

> The anxiety usually last only a week or two, but seldom persists as long a 4 weeks.

Interestingly, when used to treat depression, Lexapro often will not produce anxiety until day 14. Thereafter, anxiety can exist for 2 to 7 days before subsiding. Do you have any ideas as to why this might be?

I consider the information and insights you bring to Psycho-Babble to be invaluable. I have missed your contributions. You are in a unique position to observe real-world outcomes in the treatment of mental illness along with the prescribing practices of physicians. I particularly admire your ability to remain objective, even when fools like me challenge your conclusions. You have a gentle way about you that is particularly nurturing and accessible.

I have more questions for you. I hope you stick around for awhile.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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