Posted by Tomatheus on March 14, 2013, at 16:18:50
In reply to Re: Nardil gavis question, posted by Cee on March 14, 2013, at 15:29:36
Hi Cee,
Getting your Nardil compounded might conceivably help to improve its performance. I think that some of those who posted on the Anxiety Community's Nardil forum tried doing that with positive results. I will say that one thing that I noticed when I was taking Pfizer's film-coated Nardil was that the medication seemed to become less effective the longer I kept my pill bottle on the shelf after bringing it back from my pharmacy -- even when I was using the enteric capsules. There is some evidence to indicate that the hydrazine in Nardil tablets can undergo rapid chemical degradation when the tablets are stored in conditions with a relative humidity of at least 80 percent (Lovering et al., 1983), so there is a possibility that exposing film-coated Nardil to moisture for too long might interfere with its effectiveness. My point in mentioning all of this is to drive home the point that I want to make that it would probably be best to get your Nardil compounded right after you pick it up from your pharmacy, if that's possible. That way, if exposing Nardil to too much moisture does interfere with its effectiveness, you'll know that you did what you could to prevent that problem from happening.
Good luck with the compounded Nardil if you decide to try that.
Tomatheus
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REFERENCE
Lovering, E. G., Matsui, F., Curran, N. M., Robertson, D. L., & Sears, R. W. (1983). Hydrazine levels in formulations of hydralazine, isoniazid, and phenelzine over a 2-year period. Journal of Pharmaceutical Sciences, 72, 965-967. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/6620160
Dx: schizoaffective disorder
Treatments: Abilify & vitamin D3
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