Posted by SLS on March 26, 2013, at 13:06:58
In reply to Anafranil Day 1 is frightening!, posted by alexcanada on March 26, 2013, at 12:25:31
Hi.
Anafranil is a potent:
1. Serotonin reuptake inhibitor (SRI)
2. Norepinephrine reuptake inhibitor (NRI)
3. Anticholinergic (ACh M1 receptor antagonist)Numbers #2 and #3 act synergistically to increase "fight or flight" tone. Many of the things you describe are the direct result of these drug effects. Ritalin also acts as #2. I would experiment with discontinuing the Ritalin, as this might be making the Anafranil startup side effects worse. As these effects ease with continued treatment, you might be able to add back the Ritalin if you find it necessary. If you need the Ritalin for ADD/ADHD, and Ritalin is problematic, you can try switching to Dexedrine, Vyvanse, or Adderall. These drugs are less potent NRIs and more potent NE releasers. Focalin might be smoother than Ritalin if methylphenidate is preferred. It is likely that your heart rate will decrease somewhat, but will remain elevated relative to baseline. This is not dangerous unless your HR exceeds 120 BPM.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1041125
URL: http://www.dr-bob.org/babble/20130322/msgs/1041128.html