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Re: SSRI's and numbed emotions- Scot

Posted by poser938 on March 26, 2013, at 16:22:05

In reply to Re: SSRI's and numbed emotions » poser938, posted by SLS on March 26, 2013, at 7:26:06

Interesting. Well, my thinking has been very pessimistic these days. I've had experiences with ssri's and snri's and adderall, ritalin and mirapex. Like I've said in the past, he first month on something like adderall is amazing. They brighten my emotions, clear my thinking, increase motivation, decrease anxiety, for about a month they'd seem like the perfect medicine. Then it all goes away and it leaves me feeling like I'm hell. Mirapex was the most recent to do this at the end of 2009 and I've been stuck like this. I don't respond to normal dopamine incressing meds anymore nor can I feel antipsychotics.

Cyproheptadine fixed this in the past when adderall did this. This time with Mirapex I took it for about 5 months and slowly got better every day on it. But I slowly had to raise the dose until I got to a very high dose and had to sto taking it. Since then I've slowly gotten worse.

My idea is that cyproheptadine helped by antagonizing either the 5ht2a or 2c receptor therefore taking the brakes off dopamine release. I'm thinking I could have the same result withan ssri by downregulating those receptors instead of antagonizing.

Oh and snri's seem to delete my motions rather than numb them like ssri's. I think the longest I've taken an ssri is 4 weeks
If I remember right. And yes I just experienced emotional numbing. I've wondered where they get the idea of these meds
Promoting neurogenesis because all it seems about 2/3 of the people that take them are emotionasl numbing. Sexual dysfunction and things like that.


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URL: http://www.dr-bob.org/babble/20130322/msgs/1041137.html