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Re: FDA Warns Of Valproate In Pregancy Or Who Could » jono_in_adelaide

Posted by SLS on May 7, 2013, at 18:28:18

In reply to Re: FDA Warns Of Valproate In Pregancy Or Who Could, posted by jono_in_adelaide on May 7, 2013, at 18:07:36

> I thought this had been fairly common knowelege for a while, that valproate had a higher risk than other anticonvulsants to the unborn child?

Yes, it has been. VPA produces neural-tube defects if taken during the first trimester. VPA antagonizes folate. I don't know to what extent folic acid is effective to prevent NTD. Perhaps someone ought to look into using L-methylfolate instead.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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