Posted by SLS on May 7, 2013, at 18:28:18
In reply to Re: FDA Warns Of Valproate In Pregancy Or Who Could, posted by jono_in_adelaide on May 7, 2013, at 18:07:36
> I thought this had been fairly common knowelege for a while, that valproate had a higher risk than other anticonvulsants to the unborn child?
Yes, it has been. VPA produces neural-tube defects if taken during the first trimester. VPA antagonizes folate. I don't know to what extent folic acid is effective to prevent NTD. Perhaps someone ought to look into using L-methylfolate instead.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1043296
URL: http://www.dr-bob.org/babble/20130501/msgs/1043345.html