Posted by Bob on October 31, 2013, at 21:12:26
In reply to Re: Do antidepressants worsen your depression? » Bob, posted by SLS on October 23, 2013, at 6:47:49
> > > Generally speaking, I see no reason to dispute the existence of these adverse effects. My only caveat is that untreated depressive disorders tend to get worse over time naturally. I only skimmed your post, so I didn't see any methodologies that take this into consideration.
> > >
> > > More study. More open minds.
> > >
> > > Thanks for posting this.
> > >
> > > Some antidepressants exacerbate my depression to the point of producing suicidality. Tachyphylaxis is very dramatic with me. I experience a robust antidepressant effect for about 3 days before relapsing.
> > >
> > >
> > > - Scott
>
> > I have tried many treatments where there is an antidepressant effect literally for about a day or only hours.
>
> Me, too! Literally hours! It is a terrible disappointment when relapse occurs. Have you ever seen the movie "Awakenings"?
>
> > This has gotten much more common and more severe in recent years. My response to psychiatric drugs is very different than when I first tried them about 20 years ago.
> >
> > Bob
>
> I have no doubt that exposure to antidepressants leaves the brain changed in some way. That "poop-out" occurs at all is evidence of this. Perhaps one change involves the downregulation of serotonin autoreceptors. This could explain the development of a hypersensitivity and intolerance to a SSRI drug after it is discontinued for an extended period of time. If a case history demonstrates extremely chronic or recurrent depression, it is a good idea to consider indefinite treatment to prevent treatment resistance.
>
>
> - Scott
I have heard of the movie Awakenings with Robert DeNiro I believe. I saw it quite a long time ago, but the clinical observations shown in the movie have indeed reminded me of some of the effects I've experienced with my mental illness and the treatments I've tried. I imagine many people struggling with these issues have had the same type of thoughts as you and I have.Bob
poster:Bob
thread:1052784
URL: http://www.dr-bob.org/babble/20131025/msgs/1053482.html