Re: Nardil with Lofepramine=Serotonin Syndrome? » BrainDamage

Posted by SLS on December 31, 2013, at 6:05:23

In reply to Nardil with Lofepramine=Serotonin Syndrome?, posted by BrainDamage on December 31, 2013, at 4:42:58

Lofepramine by itself is not active as an antidepressant. However, it is a pro-drug of imipramine. Lofepramine is converted into imipramine in the liver. Imipramine thus becomes an active metabolite. Imipramine significantly inhibits the reuptake of serotonin, and is quite capable of producing a toxic serotonin reaction (serotonin syndrome) when combined with MAOIs.

- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
- George Bernard Shaw

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Nardil with Lofepramine=Serotonin Syndrome? BrainDamage 12/31/13
Psycho-Somatic??? BrainDamage 12/31/13
Re: Nardil with Lofepramine=Serotonin Syndrome? » BrainDamage SLS 12/31/13
Lofepramine=Desipramine(?) BrainDamage 12/31/13
Re: Lofepramine=Desipramine(?) » BrainDamage SLS 12/31/13
Re: Nardil with Lofepramine=Serotonin Syndrome? » BrainDamage SLS 12/31/13
Re: Nardil with Lofepramine=Serotonin Syndrome? Cee 1/3/14

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