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Switching from Abilify to Latuda - Failed

Posted by SLS on February 16, 2014, at 14:36:37

In reply to Re: Switching from Abilify to Latuda » SLS, posted by Bob on January 31, 2014, at 14:15:36

Well, Latuda was a failed treatment for me. Despite an encouraging improvement in symptoms during the first few days, Latuda made me feel very much worse over time and upon a dosage increase to 60 mg/day. I had to fight thoughts of suicide. Not fun. I have been feeling better since discontinuing Latuda two days ago. It is my suspicion that my bipolar depression was made worse by the ability of Latuda to block NE alpha-2a receptors. Other drugs with this property have exacerbated my depression in the past, including Remeron and idazoxan. My guess is that more people will profit from the 5-HT7 antagonism exerted by Latuda in the treatment of depression than will suffer an exacerbation of that illness.

Good luck to everyone being treated with Latuda!


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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